
Dilemma Foundation
A combined powder with electrolytes, magnesium, creatine, and D3 + K2. Review the full formula and total intake before combining it with other supplements.
A practical guide from Lauren Rasky
Common deficiencies to discuss with your care team, hydration essentials, and the supplement options I recommend.
Explore the guideStart with your symptoms, your labs, and your clinician’s guidance.
Many people with POTS have low circulating blood volume. A clinician-directed fluid and sodium plan can support blood volume and reduce orthostatic symptoms. This does not necessarily mean your blood sodium is low. [1]

A combined powder with electrolytes, magnesium, creatine, and D3 + K2. Review the full formula and total intake before combining it with other supplements.
Low iron stores have been reported in some people with POTS, including adolescent studies. Iron deficiency and anemia can also contribute to fatigue and rapid heartbeat. A CBC and ferritin can help guide next steps. [1, 2]

An iron formula to discuss if testing confirms low iron. The right form and dose depend on your labs and tolerance.
Shop Iron Response
Contains chelated iron (Ferrochel®). An alternative to discuss with your clinician when iron supplementation is appropriate.
Vitamin D supports bone and muscle health. Low levels can occur with or without POTS; evidence does not establish vitamin D supplements as a POTS treatment. Discuss testing if your history or risk factors suggest a need. [3]

A liquid D3 + K2 option. Choose a dose based on your vitamin D level and your clinician’s guidance.
Shop Vitamin D3 + K2
A capsule formula containing D3, K2, and other ingredients. Check the label for your total daily vitamin D intake.
B12 and folate deficiencies can cause anemia; B12 deficiency can also affect nerve function. Evaluation may be especially helpful with a restricted diet or absorption concerns. A B-complex is not a standard POTS treatment. [4]

A B-complex option. A confirmed B12 deficiency may need a specific B12 treatment plan rather than a general complex.
Shop Activated B-Complex
A B-vitamin blend with additional ingredients, including herbs. Have your clinician review the full label and medication compatibility.
Magnesium supports normal muscle and nerve function. POTS alone does not establish magnesium deficiency, and supplements are not a proven POTS treatment. Consider your diet, medical history, and tolerance first. [5]

A magnesium supplement with multiple forms. Review the elemental magnesium amount, kidney health, and medication timing with your clinician.
Nausea, bloating, constipation, and changes in stomach emptying can occur alongside POTS. Persistent symptoms deserve evaluation. They do not automatically mean poor nutrient absorption or an enzyme deficiency. [6]

A plant-based digestive enzyme option. Discuss whether enzymes fit the cause of your symptoms before adding them.

A digestive enzyme blend. It is not a treatment for POTS or delayed stomach emptying.
Personalized support
You don’t need every supplement on this page. Your symptoms, diet, medications, and lab results can help your care team decide what actually fits.
Explore wellness coachingBring this to your next appointment
Ask about: your fluid and sodium targets; whether a CBC and ferritin are appropriate; B12 or folate testing based on your history; and vitamin D testing when indicated.
Bring: your medication and supplement list, recent labs, and notes about your symptoms, meals, and digestion.
Keep it simple: select products with your clinician and avoid overlapping ingredients.
Good questions to ask
No. A POTS diagnosis does not mean you have every deficiency listed. Your clinician can help decide what to test and whether a supplement is useful.
It combines electrolytes, magnesium, creatine, and D3 + K2. Its sodium content may cover only part of your prescribed daily target. Review the label before adding separate magnesium or vitamin D products. Creatine is included in the formula, but is not an established POTS treatment.
Tell your clinician, especially with ongoing nausea, vomiting, weight loss, or trouble eating. The cause of the symptoms matters. An enzyme blend is not a substitute for evaluating stomach emptying or other digestive conditions.
Use LAUREN10 for Dilemma Nutrition, RASKY10 for BIOptimizers, and OHSRASKY as your Optimal Health Systems referral code. Codes are supplied by Lauren; promotions and availability can change. Review the discount or referral entry before completing checkout.
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